Indlela yokusebenza ye-chondroitin sulfate (CS)
1. Ukwengeza ama-proteoglycans ekulungiseni uqwanga oluhlangene.
2. Inomphumela oqinile wokukhipha amanzi emzimbeni futhi ingadonsa amanzi kuma-molecule e-proteoglycan, okwenza uqwanga lube ugqinsi njengesipontshi, lunikeze amanzi nezakhamzimba ku-cartilage, luthuthukise ukwakheka koqwanga, ngaleyo ndlela ludlale indima yokushaqeka nokuthambisa, futhi waziwa ngokuthi “umazibuthe owuketshezi”.
3. Ukuvikelwa kwe-cartilage ngokuvimbela isenzo sama-enzyme "adla uqwanga" (isb. i-collagenase, i-histoproteinase).
4. Yehlisa ubuhlungu, ukuvuvukala nokuqina futhi ithuthukise umsebenzi wokunyakaza kwamalungu.
I-Chondroitin sulfate (CS) ihlanganiswe ne-glucosamine (GS)
● I-Chondroitin sulfate (CS) isheshisa inqubo yokungena kwe-glucosamine sulfate esihlanganyelwe, futhi inhlanganisela yakho kokubili iphumelela kakhulu ekulungiseni uqwanga oluhlangene nokubuyisela uqwanga olonakele.
●Inhlanganisela ye-GS ne-CS ingathuthukisa ukuvinjelwa kokukhiqizwa kwabalamuli abahlukahlukene abavuthayo kanye nama-radicals angenayo umoya-mpilo ezicutshini ezihlangene, ivimbele umsebenzi we-metalloproteinase futhi izinze ulwelwesi lwe-lysosomal, ngaleyo ndlela inikeze imiphumela elwa nokuvuvukala ne-analgesic. Ukuhlanganiswa kokubili kungabuye kukhuthaze ukuhlanganiswa kwe-proteoglycans kanye ne-collagen ku-articular cartilage tissue, ukugcina ukuzinza kwe-matrix ye-cartilage extracellular, futhi futhi ngokungaqondile ibambe iqhaza ekuqedeni ukuvuvukala nokukhulula ubuhlungu.
● Ukubhekwa komtholampilo kubonisa futhi ukuthi ekwelapheni iziguli ezilinganiselwe nezinzima, umphumela ohlangene we-GS ne-CS uphakeme kunomuthi owodwa, onganciphisa ngempumelelo ubuhlungu beziguli.
Isikhathi sokuthumela: Nov-19-2022